The ATXN3 Polyclonal Antibody from MyBioSource.com is a Goat Polyclonal antibody to Ataxin 3, and ATXN3. This antibody recognizes Human, Mouse, Rat, Canine, and Non-Human Primate antigen. The ATXN3 Polyclonal Antibody has been validated for the following applications: Western Blot.
Description
Goat polyclonal antibody to ATXN3. This protein appears to be a component of the ubiquitin proteasome system and has deubiquitinase activity. It may also have roles in neuroprotection, protein homeostasis maintenance, transcriptional and cytoskeleton regulation, myogenesis and degradation of misfolded chaperone substrates. The protein contains Qn repeats in the coding region, and the expansion of these repeats from the normal 13-36 to 68-79 is one cause of Machado-Joseph disease also known as spinocerebellar ataxia-3, an autosomal dominant neurologic disorder